ADVANCES IN FRIEDEL-CRAFTS ACYLATION REACTIONS

Used in the production of a wide number of fine chemicals and pharmaceuticals, the Friedel-Crafts acylation reaction represents a synthetic process of great interest to organic chemists of academia and industry. This book focuses on how to make this reaction more economically and environmentally friendly by using green acylating conditions, minimizing the formation of waste and decreasing production costs. Incorporating examples of all acid-catalyzed Friedel-Crafts acylation reactions, the text considers classic Lewis and Brönsted acid types along with more innovative and advanced multicomponent superacid catalysts. The book emphasizes the major industrial applications, providing a critical assessment of the differences, advantages, and disadvantages of homogeneous and heterogeneous catalysis.